Immune-related tumour response assessment criteria: a comprehensive review

Immune-related response criteria: light and shadows

Correspondence to Dr Marco Merlano; [email protected] Researchers realised that standard criteria for response assessment are unsuitable for immunotherapy. They observed that: (1) time to response may be longer for immunotherapy; (2) response may occur after an initial pseudoprogression; (3) discontinuation of treatment may be inappropriate in case of progressive disease (PD) unless PD is con...

Fatigue Assessment Scales: A comprehensive literature review

Background & Aims of the Study: Fatigue is one of the most important issues relating with safety and other aspects of human life. To understand fatigue and its relative factors and causes, there is a need to useful instruments, such as self-reported scales. The purpose of this study is to identify and present useful self-reported scales to measure fatigue. Materials & Methods: Data were extrac...

A comprehensive review on vitamin D receptor (VDR) gene polymorphism in immune-related diseases with emphasis on dermatologic disorders

There are many immune mediated disorders with the corroborated role of vitamin D or Vitamin D Receptor (VDR) gene polymorphisms in their pathogenesis, immunologic regulation, and disease characteristics. Therefore, in this review, we searched PubMed data base in regard to the role of VDR gene polymorphisms in common autoimmune disorders, emphasizing on dermatologic diseases.

1070padaptation of the Immune Related Response Criteria: Irrecist.

Developing a common language for tumor response to immunotherapy: immune-related response criteria using unidimensional measurements.

PURPOSE Immune-related response criteria (irRC) was developed to adequately assess tumor response to immunotherapy. The irRC are based on bidimensional measurements, as opposed to unidimensional measurements defined by Response Evaluation Criteria in Solid Tumors, which has been widely used in solid tumors. We aimed to compare response assessment by bidimensional versus unidimensional irRC in p...